Cationic N-Heterocyclic Carbenes for Mmaterials Chemistry and Sustainable Catalysis
CHEMISTRY & GREEN CHEMISTRY
Duration: NanoX master Internship (8 months part-time in-lab immersion)
Latest starting date: 01/10/2022
Localisation: Laboratoire de Chimie de Coordination (LCC)
CNRS - UPR 8241
205, route de Narbonne
31077 Toulouse Cedex 04, France
This research master's degree project could be followed by a PhD
From mere laboratory oddities, N-Heterocyclic Carbenes (NHCs) have been elevated to compounds of tremendous practical significance in catalysis and synthetic chemistry, with new and exciting applications across the chemical sciences. This ever-growing success is directly related to their unique stereo-electronic properties and the search for new carbenic structures has thus become a priority in order to broaden their application scope. In line with our research interests, we propose to develop cationic NHCs, in which the cationic charge would be directly connected to the carbenic center, in order to maximize the electronic and charge-effects. Interest and impact of these species could be gauged in light of the outstanding results obtained with their phosphine analogues, namely cationic phosphines. A proof of concept, we recently reported the cationic NHC 1+ bearing a N-bounded 2,3-bis(diisopropylamino)cyclopropenium group.
 M. N. Hopkinson, C. Richter, M. Schedler, F. Glorius, Nature 2014, 510, 485.  (a) M. Ruamps, N. Lugan, V. César, Organometallics 2017, 36, 1049; (b) Y. Canac, Chem. Asian J. 2018, 13, 1872; (c) M. Ruamps, S. Bastin, L. Rechignat, A. Sournia-Saquet, D. A. Valyaev, J.-M. Mouesca, N. Lugan, V. Maurel, V. César, Chem. Commun. 2018, 54, 7653; (d) M. El Kadiri, A. Chihab, R. Taakili, C. Duhayon, D. A. Valyaev, Y. Canac, Organometallics 2022, 41, 456.  M. Alcarazo, Acc. Chem. Res. 2016, 49, 1797.  C. Barthes, C. Duhayon, Y. Canac, V. César, Chem. Commun. 2020, 56, 3305-3308.
Areas of expertise:
Carbenes, ligand design, coordination chemistry, cations, redox-activity, energy storage, homogeneous catalysis, materials, DFT calculations
Required skills for the internship:
Good knowledge in organic chemistry, organometallic chemistry, and advanced characterization techniques (multinuclear NMR, X-Ray diffraction, MS, EPR spectroscopy …). Schlenk line technique, glove box.